Email: OSTEINBERG@HOSTOS.CUNY.EDU
 

Office Number: A507c

Office Tel: 718-518-4130

Courses Teaching:

BIO110 Principles of Biology
BIO310 Microbiology
BIO299 Independent Studies in Biology

Publications:

Shastry, S, Steinberg-Neifach, O., Lue, N., Stone, M.D.  (2018) Direct observation of nucleic acid binding dynamics by the telomerase essential N-terminal domain. Nucleic Acids Research, 46:3088-3103
Steinberg-Neifach O and N. F. Lue (2015) Telomere DNA recognition in Saccharomycotina yeast: potential lessons for the co-evolution of ssDna and dsDna-binding proteins and their target sites. Frontiers in Genetics 6:162. doi: 10.3389/fgene.2015.00162. eCollection
 
Steinberg-Neifach O, Wellington K, Vazquez L, Lue NF. (2015) Combinatorial recognition of a complex telomere G-strand repeat sequence by the Candida parapsilosis Cdc13AB heterodimer. Nucleic Acids Research, 43: 2164-2176
 
Steinberg-Neifach O, Wellington K, Vazquez L, Lue NF. (2015) Combinatorial recognition of a complex telomere G-strand repeat sequence by the Candida parapsilosis Cdc13AB heterodimer--we are having twins! In: Telomeres and Telomerase, Ed. Cooper, J., , V. Lundblad, T. deLange, and R. Reddel. Cold Spring Harbor Press, Cold Spring Harbor, NY p. 155
 
Wellington, K., Vazquez, L., DeJesus, V.,  Davila, K., Steinberg Neifach, O., and Neal F. Lue.. (2014) Efficient Binding of Candida parapsilosis Cdc13 Proteins to Telomeres Require Heterodimer Formation. ABRCM conference,  November 12-15, 2014, san Antonio, USA

Lue NF, Zhou R, Chico L, Mao N, Steinberg-Neifach O, and T. Ha (2013) The telomere capping complex CST has an unusual stoichiometry, makes multipartite interaction with G-Tails, and unfolds higher-order G-tail structures.  PLoS Genet.;91:e1003145. doi:
 
Lidia Chico, Olga Steinberg Neifach, Ninghui Mao, and Neal F. Lue. 2011. Biochemical and Genetic Analysis of the STN1-Ten1Complexes from Candida Species. In: Telomeres and Telomerase, Ed.: de Lange, T., Reddel,. R. , Shippen, D.,  and Zakian, V. Cold Spring Harbor Press, Cold Spring Harbor, NY p. 49

Yu, E.Y, Yen, W.F.,2010. Rap1 in Candida albicans: an Unusual Structural Organization and a Critical Function in Suppressing Telomere Recombination. Molecular Biology of the Cell  30:1254-1268 Epub 2009 Dec 14

Steinberg, Olga and Neal Lue. 2009. Analysis of the regulatory role of the N-terminal domain of Candida albicans telomerase reverse transcriptase. In: Telomeres and Telomerase, Ed. J. Lingner, D. Shippen, and Zakian, V.. Cold Spring Harbor Press, Cold Spring Harbor, NY p. 163

Yu, E.Y., Steinberg-Neifach, O., Dandjinou, A., Kang, F., Morrison, A.J., Shen, X., and N.F. Lue. 2007. Regulation of telomere structure and functions by subunits of the INO80 chromatin remodeling complex. Molecular Biology of the Cell  27: 5639-5649

Steinberg-Neifach, O., Den, A., Naglik, R.J., Hohl, T., and N.F. Lue. 2007. Telomerase deficiency and virulence in Candida albicans. In: Telomeres and Telomerase, Ed. J. Lingner, V. Lundblad, and D. Shippen. Cold Spring Harbor Press, Cold Spring Harbor, NY p. 157

Yu, E.Y., Steinberg-Neifach, O., Dandijinou, A., Kang, F., Morrison, A.J., Shen, X., and N.F.Lue. 2007. Regulation of telomere structure and functions by subunits of the INO80 chromatin remodeling complex. In: Telomeres and Telomerase, Ed. J. Lingner, V. Lundblad, and D. Shippen. Cold Spring Harbor Press, Cold Spring Harbor, NY p.187

Lue, N.,  Hsu, M. Yu, E.Y., Dandjinou, A., Den, A., and O. Steinberg-Neifach. 2007. Telomerase from Candida albicans protects telomeres against aberrant degradation in vivo and exhibit a primer extension activity that is dependent on regulatory proteins in vitro. In: Telomeres and Telomerase, Ed. J. Lingner, V. Lundblad, and D. Shippen. Cold Spring Harbor Press, Cold Spring Harbor, NY p.  9

Steinberg Neifach, O., and N.F. Lue. 2006. Modulation of telomere terminal structure by telomerase components in Candida albicans. Nucleic Acids Research 34: 2710-2722.

Korolyev, E., Steinberg-Neifach, O., and D. Eshel. 2005. Mutations in the yeast kinesin-like Cin8p are alleviated by osmotic support. FEMS Microbiology Letters, 244: 379-383.

Steinberg, O., Granitto, S., Xi,  Z., Murray, D., and N.F. Lue. 2005. The conserved TPR Domain of the yeast telomerase protein Est1p is both an RNA- and protein-interaction domain. In: Telomeres and Telomerase. Ed. T. De Lange, J. Lingner, and V. Lundblad. Cold Spring Harbor Press, Cold Spring Harbor, NY p. 133

Ciudad T., Andaluz, E., Steinberg Neifach, O., Lue, N.F., Gow, N.A., Calderone, R.A., and  G. Larriba. 2004. Homologous recombination in Candida albicans: role of CaRad52p in DNA repair, integration of linear DNA fragments and telomere length. Molecular Microbiology, 53:1177-1194.

Steinberg-Neifach, O., Sing, S., and N.F. Lue. 2004. Telomere structure in Candida albicans. The FASEB Journal, 18.8: 35.9

Lue, N.F., Peng, Y., Lin, Y-C., Bosoy, D., Steinberg, O. 2004. Analysis of telomerase processivity: structural determinants and physiological significance. The FASEB Journal, 18. 8: 124

Singh, S.M., Steinberg Neifach, O., Mian, I.S., and  N.F. Lue. (2002) Analysis of telomerase in Candida albicans: potential role in telomere end protection. Eukaryoic  Cell, 1:967-77.

Steinberg Neifach, O. and D. Eshel. (2002) Heterozygosity in MAT locus affects stability and function of microtubules in yeast. Biology of the Cell. Jun; 94(3): 147-56.

Steinberg Neifach, O., Braunstein, M.J., and D.Eshel. (2001) Rapid assessment of budding pattern by cell morphology in yeast Saccharomyces cerevisiaeBio Technology. 3:482, 484, 486

Areas of Expertise:
Molecular Biology, Microbiology, Genetics.

Areas of Interest:
Chromosomal ends structure and regulation